Market Size (2017)
2017
$208.64M
Vertical: HealthcareBase Year: 201912 Sections
Market Size (2017)
2017
$208.64M
Projected (2027)
2027
$279.41M
CAGR (2017–2027)
3.0%
3.0%Key Players
109+
Ultra-low temperature freezers are bio-coolers whose temperature ranges from -40°C, -86°C down to -150°C. The growth and development in the research sector such as biomedical and life sciences and increasing demand for blood bank storage lead to the market growth of ultra-low temperature freezers. These ULT freezers are also used on a large scale by pharmaceutical companies for drug discovery and clinical testing processes. These are also used to preserve drugs, chemicals, viruses, bacteria, enzymes, cell preparations, and tissue samples. The development of energy-saving ultra-low temperature freezers is expected to create future opportunities in this market.
The market is segmented on the basis of type, degree of cooling, application, end user, and region. Based on type, the market is segmented into upright ULT freezers and chest ULT freezers. The upright ULT freezers are further sub-segmented into floor standing and benchtop/undercounter. On the basis of the degree of cooling the ULT freezers are segmented into -41°C to -86° C Freezers and -87°C to -150° C Freezers. By application, the market is segmented into blood & blood products, biological samples, drug compounds, and others. On the basis of end user, the market is segmented into biobanks, hospitals and clinics, academic and research institutes, and others. Geographically, it has been analyzed across North America, Europe, Asia-Pacific, and the Middle East and Africa.
The key players that operate in the market include Thermo Fisher Scientific Inc., Helmer Scientific, Stirling Ultracold, Global Cooling Inc., Eppendorf AG., VWR International, PHC Corporation, Esco Micro Pte Ltd., BINDER GmbH, Labcold, and Arctiko. The key factors that drive the ultra-low temperature freezers market are increasing research and development using tissue culture technology, growing blood banks, and rising adoption of new technology in healthcare. However, factors such as high costs of ultra-low temperature freezers hinder market growth.
The Ultra Low Temperature Freezer Market market is projected to grow at a CAGR of 3.0% from 2017 to 2027.
Historical performance and future projections (2020–2030, USD Billion)
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View Subscription PlansMarket Size (USD Mn)
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View Subscription PlansThe scope of the global ultra-low temperature freezers market study includes market size analysis and a detailed analysis of the manufacturer’s products and strategies. The market has been segmented based on type, degree of cooling, application, end user, and region.
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View Subscription PlansThis report applies a rigorous multi-stage research process combining primary interviews, secondary data sources, and bottom-up market modelling to ensure accuracy and completeness across all segments and geographies.
Base Year
2019
Historical Period
2017 – 2019
Forecast Period
2019 – 2027
Primary Interviews
150+
Historical data (2017–2019) and forecast period (2019–2027)
Our research process spans primary interviews with industry stakeholders combined with comprehensive secondary data analysis, validated through triangulation across multiple independent sources.
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View Subscription PlansThreat of New Entrants
The threat of new entrants is moderate in the global ultra-low temperature freezers market. Any ultra-low temperature freezer manufacturing company trying to enter the market is required to accept or abide by the mandatory regulatory standards. However, the budget required for research and development of a product is low as compared to other industrial equipment. Ultra-low temperature freezer is manufactured for use in the storage of various pharmaceutical products, biological samples, chemicals, flammable materials, and others. Moreover, the majority of consumers are using products of trusted sellers. The consumers are likely to prefer established brands over new market players due to quality concerns, product efficiency, and storage capacity of the freezers, which does not comfort the new entrants to enter the market easily.
Bargaining Power of Suppliers
The suppliers in the global ultra-low temperature freezers market are finished goods manufacturers. There are various suppliers present in the global ultra-low temperature freezers market. The switching cost of these suppliers is moderate due to the high competition, and also the consumers are slightly inclined towards branded products. The suppliers are likely to enter into long term partnerships with research institutes, biobanks, and pharmaceutical & biotechnology companies. However, low-quality products are likely to damage the quality of the temperature-sensitive samples, and it can cause adverse effects on the ongoing research process. Hence, consumers are selective about suppliers depending on the usage of freezers and storage of items. Due to this, the overall bargaining power of suppliers in the global ultra-low temperature freezers market is low.
Threat of Substitutes
The threat of substitutes in the global ultra-low temperature freezers market is expected to be low as there are relatively low substitutes available for storing temperature-sensitive items for a long period. The potential substitutes can be conventional freezers and laboratory freezer. These freezers have low storage capacity and the technology used in it is obsolete for the current market requirement. Where in, ultra-low freezers are cost-effective, suitable for bulk sample storage, and have advanced technology used, therefore consumers favor these freezers comparatively more. Hence, the high degree of product differentiation decreases the threat of substitutes. Hence, due to the above factors the threat of substitutes is low in the market.
Bargaining Power of Buyers
The bargaining power of buyers is moderate in the global ultra-low temperature freezers market. The number of buyers is more as compared to the number of ultra-low temperature freezer manufacturing companies. However, the ultra-low temperature freezer is specialized and plays an important role in pharmaceutical product storage, and the buyers of the ultra-low temperature freezer are moderately inclined towards advanced products manufactured by key companies. Most of the buyers are bio-banks, hospitals, and research organizations; they are likely to enter into the long-term agreements with the ultra-low temperature freezer manufacturers for uninterrupted service. Moreover, there is an exert pressure on the manufacturers due to the low switching cost and intense rivalry in the market, which is responsible for the moderate bargaining power of buyers.
Intensity of Rivalry
The rivalry in the global ultra-low temperature freezers market is high. A large number of ultra-low temperature freezer manufacturers increases the intensity of rivalry in the market. The market is growing with a prominent growth rate and likely to provide opportunities for major players to expand their geographical boundaries which will initiate tough competition between major players to capture maximum market share in the emerging markets. The players in the market are engaged in developing a process to lower their manufacturing and logistics costs to increase profitability and to overcome the competition. In addition, they also focus on developing advanced product features for differentiating their brand from its competitors.
Market estimates by geography (2027)
InsightAmericas leads with $407.73M by 2027, while Asia Pacific is projected to grow fastest at a 3.7% CAGR.
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View Subscription Plans| REGION | 2017 | 2019 | 2027 | CAGR | SHARE |
|---|---|---|---|---|---|
| Europe | $208.64M | $237.50M | $279.41M | 3.0% | 28% |
| Asia Pacific | $166.37M | $195.28M | $240.24M | 3.7% | 24% |
| Middle East and Africa | $56.11M | $58.90M | $62.06M | 1.0% | 6% |
| Americas | $313.81M | $353.59M | $407.73M | 2.7% | 41% |
| Total | $744.93M | $845.27M | $989.44M | 3.0% | 100% |
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View Subscription PlansTotal Market Size
$989.43M
| APPLICATION | REVENUE ($B) | GROWTH RATE | MARKET PENETRATION |
|---|---|---|---|
| Upright | $723.14M | 3.0% | 72% |
| Chest | $266.29M | 3.0% | 87% |
* Revenue projections based on 2025 estimates. Growth rates represent CAGR 2024–2030. Market penetration indicates current adoption rate within addressable market segments.
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Analytical insights on Ultra Low Temperature Freezer Market covering market dynamics, competitive landscape, and strategic outlook.
The Ultra Low Temperature Freezer Market market is projected to reach $279.41M by 2027, growing at 3.0% CAGR. The Upright segment holds the largest share.
Ultra-low temperature freezers (ULT freezers) are types of bio-freezers that are used for the preservation of viruses, bacteria, drugs, enzymes, chemicals, cell preparations, and tissue samples among others. They generally have a temperature range of -40°C, -86°C down to -150°C. Factors such as the growing demand for ultra-low temperature freezers, raising awareness and improving technology, alternative refrigeration cycles, demand for environment-friendly refrigerators, and increasing biomedical R&D spending in Asian countries drive the global market for ultra-low temperature freezers. However, factors such as high equipment cost, and heavy maintenance and ethical issues related to embryo freezing are estimated to restrain the market growth.
From the past few years, the demand for ULT freezers and refrigerators has significantly increased owing to the growing need for storing enzymes, cell preparations, viruses, bacteria, drugs, chemicals, and tissue samples, among others. The rising research and development in the biomedical industry are also attributing to market growth. Most of the enzymes and chemicals are temperature sensitive so to maintain their property and continue its usage in various research activity it has to be stored at low temperatures to maintain its property.
In 2016, the government of France announced a program, namely, the “Medecine Genomique 2025”. This program aims to open 12 genome sequencing centers in France. Thus, the increasing number of research centers in the healthcare industry drives market growth. Additionally, the growing prevalence of chronic and infectious diseases is generating a parallel demand for personalized drugs, biologics, and blood preservation. As per the National Center for Biotechnology Information (NCBI) in 2016, it was estimated that approximately 40,829 hematopoietic stem cell transplantations were performed across European countries. Considering such trends, the demand to store easily perishable biological articles such as stem cells is estimated to boost the market growth.
The use of ULT freezers requires time to time maintenance. If the maintenance of ULT freezers is not done on time, the performance of the freezer would eventually be hampered. According to an audit conducted by the University of Cambridge (The Cambridge Green Challenge), it was found that many of the ULT freezers were consuming too much energy and money. Therefore, the cost of maintenance is high. For instance, an old and inefficient freezer can cost greater than USD
1226.19 per annum in electricity, compared to less than
USD 367.86 for Eppendorf Cryocube F570h. Thus, the high cost of operation is seen as a barrier to the acceptance of ULT freezers.
Additionally, The US Environmental Protection Agency (EPA) requires laboratory-grade refrigerator and freezer efficiency levels and product specification information on its ENERGY STAR website. Manufacturers require to meet the guideline and get a list of ENERGY STAR-certified laboratory-grade freezers and refrigerators.
The cold packing and shipping of the biomaterial produce a large number of waste materials. The multiple freeze-thaw cycles lead to quality degradation of the samples as cold freezing especially of bio-tissues can lead to cell membrane damage. Sometimes due to power failure or freezer failure the samples kept in the freezer are put at risk for degradation and loss. In academic institutes where there is a large number of samples required to be kept in the freezers, the freezers take up an increasingly large amount of lab space, potentially inhibiting current and new facility/research space needs. The heat generated from refrigerators/freezers further adds demands to facility requirements along with costs and planning to stabilize environmental conditions at low temperatures. Due to this the maintenance costs and energy costs of cold refrigerators/freezers add up as sample collection grows and accelerates as the cost of energy increases.
Near-term growth will likely concentrate in modular bioreactor lines and closed-system media workflows that shorten validation cycles while preserving batch traceability.
Partnerships between CDMOs and instrumentation vendors should accelerate standard datasets for comparability across sites, improving forecasting models used in capacity planning.
Longer horizon, organoid and microphysiological adoption may reshape segment mix; teams that invest early in assay interoperability and cloud QC hooks are better positioned to capture upside without fragmenting their analytics stack.
Profiles of 109 companies operating in the Ultra Low Temperature Freezer Market market, including revenue, employee count, and market positioning where available.
Showing 109 of 109 companies
A/S Vestfrost Solutions
Company Headquarters: Europe, Denmark Founded: 1963 Workforce: ~201-250 Company Working: A/S Vestfrost Solutions is an international company involved in the development and manufacturing of innovative and efficient refrigerators and freezers for the healthcare industry. The company was founded in Esbjerg, Denmark in 1963 to develop the world’s best refrigerators and freezers. In 2010 the company acquired a local cooler manufacturer in Csongrád, Hungary. A/S Vestfrost operates through its main four business segments, which include biomedical, cold chain, merchandising, and wine.
Helmer Scientific
Company Headquarters: Indiana, US Founded: 1977 Workforce: 201-500 Company Working: Helmer Scientific (Helmer) is a well-established and growing company in the field of medical devices. The company is involved in designing, integrating, manufacturing, marketing, and distributing specialized medical and laboratory equipment to clinical and life science customers all around the globe. It offers various industry-leading products for pharmaceutical storage. The products offered by the company serve medical field customers such as hospital laboratories, pharmacies, clinics, health departments, and research facilities. The products that are developed focus on the safety of blood products, medications, reagents, samples, and more. The company has its distribution channels in more than 125 countries all around the globe.
Eppendorf AG
Company Headquarters: Hamburg, Germany Founded: 1945 Workforce: 3367 Company Working: Eppendorf AG (Eppendorf) is a leading life science company that is engaged in the development of instruments, consumables, and services for liquid, sample, and cell handling in laboratories all around the globe. It offers a wide range of products that include pipettes and automated pipetting systems, spectrometers, dispensers, centrifuges, mixers, and DNA amplification equipment as well as ultra-low temperature freezers, bioreactors, CO2 incubators, fermenters, shakers, and cell manipulation systems. With these products, it serves various industries such as pharmaceutical, biotechnology, chemical, and food. The company focuses on clinical and environmental analysis laboratories, forensics, and industrial laboratories performing process analysis, production, and quality assurance. Geographically, it operates in more than 25 countries in regions such as Europe, North America, and Asia.
Arctiko
Company Headquarters: Syddanmark UK Founded: 2002 Workforce: ~120 Company Working: Arctiko is a medical device manufacturing company involved in manufacturing products such as freezers and refrigerators for the biomedical and life science sectors, including laboratories, blood banks, and hospitals. The company is specialized in various biotechnology products, such as ultra-low temperature freezers (-86°C and -90°C), biomedical freezers and refrigerators, cryogenic freezers (-150°C), Arctiko controller G214, cold storage rooms, blood bank refrigerators (+4°C), and single compressor technology. The company’s primary aim is to create user-friendly freezers to be used in biomedical and pharmaceutical industries globally. The products offered by the company are distributed to more than 90 countries around the world.
LABCOLD
Company Headquarters: Hampshire UK Founded: 1932 Workforce: ~50 Company Working: LABCOLD was earlier known as Boro Dairy Laboratories. Earlier, the company used to provide a laboratory analytical service to London’s small dairy suppliers. In 1946, the company moved to Catford, and developed its laboratory equipment business, and also started supplying specialist temperature control equipment used in medical, food, pharmaceutical, and life science industries. It offers refrigeration products such as pharmacy refrigeration, laboratory refrigeration, blood product storage, and technical services.
Esco Micro Pte Ltd
Company Headquarters: Singapore, US Founded: 1978 Workforce: 1000 Company Working: Esco Micro Pte Ltd. (Esco) is a biotechnology company involved in developing and manufacturing laboratory, medical, and pharmaceutical equipment solutions. The company operates through three segments and offers products that include laboratory equipment, medical equipment, and pharmaceutical equipment. It manufactures biological safety cabinets, lab incubators and ovens, CO2 incubators, fume hoods, ductless fume hoods, laminar flow cabinets, ultra-low temperature freezers, hospital pharmacy isolators, and containment/pharma products, which are used in more than 100 countries. Geographically, it operates from countries such as the US, the UK, Germany, Italy, Russia, Singapore, China, and India.
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Ultra Low Temperature Freezer Market